Neurological: Key Points

Incidence: Approx 3500 cases p.a. in England & Wales
Age: Rare below 30 years – but relatively evenly
distributed thereafter (peak at age 60 – 69 years).

Patients with brain tumours typically present with one of the following:

  • Progressive neurological deficit (e.g. progressive weakness, sensory loss, dysphasia, ataxia) developing over days to weeks.
  • Seizure disorder.
  • Raised Intracranial Pressure (headache, vomiting, papilloedema).
  • Cognitive/personality (mental state) changes.

Prevalence among patients presenting with brain tumours:

  • Focal neurological deficit > 50 %
  • Seizures 25-30%
  • Headaches 25-35%
  • Papilloedema 23-50%
  • Mental changes 16-20%

The probability of having a brain tumour in the following situations is as follows:

  • New onset seizure disorder (any type) in adults 2-6%
  • New onset status epilepticus 10 %
  • Headache of non-migrainous type < 1%

 

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